Figure 1: General features of type IIA and IIB topoisomerases. To address these and other outstanding issues, we have determined the structure of a full-length type II topoisomerase, Methanosarcina ...
Protein phosphatase 2A (PP2A) is a major Ser/Thr phosphatase; it forms diverse heterotrimeric holoenzymes that counteract kinase actions. Using a peptidome that tiles the disordered regions of the ...
Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus. The ...
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